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Ames Test

Mouse Lymphoma Assay

Chromosome Aberration Test

Micronucleus Test

Rat Liver UDS Test

Comet Assay

ICH and FDA recommendations

Links

Introduction to
GENETIC TOXICOLOGY



Associations and Agencies

Genetic Toxicology Association


Journals

European Journal of Genetic Toxicology
Mutation Research


Ames Test

Ames test, Wikipedia entry
Microbial Genetics


Mouse Lymphoma Assay

US FDA Red Book
Evaluation of the mouse lymphona assay [...]
NIH Summary


Chromosome Aberration Test

Summary of the chromosome aberration test


Micronucleus Test

NIH Summary


Rat UDS Test

Interpretation of results


Contract Research Organizations

Safepharm Laboratories - UK

BioReliance - Worldwide
  • Ames Test
  • Mammalian Cell Gene Mutation Assays
  • Chromosome Damage
  • In Vitro Cytogenetics
  • In Vivo Cytogenetics
  • Primary DNA Damage
  • DNA Damage and Repair
  • Cell Transformation
  • In Vitro Mammalian Cell Transformation Assays (new -SHE Assay )
  • In vivo Comet Assay
  • In vitro Comet Assay
  • Assessment of Hemolytic Property
  • Mammalian S9 Microsome Preparations
ITT Research Institute - USA
  • Ames Test
  • In Vitro and In Vivo Micronucleus Assays - Mouse, Rat (Bone Marrow and Peripheral Blood)
  • Mouse Lymphoma
  • Cytotoxicity Assay
Research Toxicology Center (RTC) - Italy
  • Ames Test
  • Mammalian Cell Mutation
  • Chromosome Aberration Tests
  • in vivo micronucleus
  • UDS assays.
Charles River - Worldwide